Effects of Epidurally Administered Ropivacaine Concentration on the Hemodynamic Parameters

Phase 4 Completed 120 enrolled Pusan National University Hospital

RandomizedParallel-groupDouble-blindBasic science

Summary

In this trial, the investigators intend to examine whether the concentration of local anesthetics during epidural analgesia could be modulating factor for change of hemodynamics in patients undergoing major upper abdominal surgery.

Timeline

Start: 2011-11-16
Primary completion: 2013-04-19
Completion: 2013-04-19

Publications

Hong JM, Lee HJ, Oh YJ, Cho AR, Kim HJ, Lee DW, Do WS, Kwon JY, Kim H. Observations on significant hemodynamic changes caused by a high concentration of epidurally administered ropivacaine: correlation and prediction study of stroke volume variation and central venous pressure in thoracic epidural anesthesia. BMC Anesthesiol. 2017 Nov 16;17(1):153. doi: 10.1186/s12871-017-0444-x.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ropivacaine	Other / unclassified	0.2 %	Other
Comparator	Ropivacaine	Other / unclassified	0.375 %	Other
Comparator	Ropivacaine	Other / unclassified	0.75 %	Other

Indications

No indication recorded.