drugset / Trial / NCT01566643
Rabeprazole Based Sequential-Concommitant Hybrid Therapies for H. Pylori Infections
Phase 4
Unknown
231 enrolled
Buddhist Tzu Chi General Hospital
Kaohsiung Medical University · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This prospective controlled randomized open-label clinical trial is designed to determine the optimal eradication rate of rabeprazole based sequential-concommitant hybrid therapies for adults infected with Helicobacter pylori in Eastern Taiwan. Enrolled patients will receive 3, 5 or 7 days of pre-concommitant (sequential part) treatment with rabeprazole + amoxicillin, then 7 days of concommitant treatment with rabeprazole + amoxicillin + clarithromycin + metronidazole.
Timeline
- Start
- 2011-01
- Primary completion
- 2012-12
- Completion
- 2012-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amoxicillin | Other / unclassified | 1 g | — |
| Subject | Clarithromycin | Small molecule | 0.5 g | — |
| Subject | Metronidazole | Small molecule | 0.5 g | — |
| Subject | Rabeprazole | Small molecule | 20 mg | — |