The Influence of Amitriptyline on Learning in a Visual Discrimination Task

Completed 32 enrolled Dieter Kunz, MD

RandomizedParallel-groupTriple-blind

Summary

The purpose of this study is to determine whether 75 mg amitriptyline affect the sleep dependent consolidation of procedural memory (visual discrimination task, Karni-Sagi-paradigm).

Timeline

Start: 2008-08
Primary completion: 2009-05
Completion: 2009-05

Publications

Goerke M, Cohrs S, Rodenbeck A, Kunz D. Differential effect of an anticholinergic antidepressant on sleep-dependent memory consolidation. Sleep. 2014 May 1;37(5):977-85. doi: 10.5665/sleep.3674.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Amitriptyline	Small molecule	75 mg	—

Indications

No indication recorded.