drugset / Trial / NCT01567657
Safety Study of Two Regimen for Sedation for Transesophageal Echocardiography
RandomizedSingle-groupSingle-blind
Summary
The purpose of this study is to determine whether sedation with a combination of pethidin hydrochlorid plus midazolam intravenously (i.v.) is superior to propofol i.v. alone in relation to blood pressure drops during an transesophageal echocardiographic examination (TEE).
Timeline
- Start
- 2012-01
- Primary completion
- 2013-01
- Completion
- 2013-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Midazolam | Small molecule | 1 mg | Intravenous |
| Comparator | Midazolam | Small molecule | 2 mg | Intravenous |
| Comparator | Midazolam | Small molecule | 7 mg | Intravenous |
| Comparator | Propofol | Small molecule | 10 mg | Intravenous |
| Comparator | Propofol | Small molecule | 20 mg | Intravenous |
| Comparator | Propofol | Small molecule | 30 mg | Intravenous |
| Comparator | Propofol | Small molecule | 40 mg | Intravenous |
| Comparator | Propofol | Small molecule | 50 mg | Intravenous |
| Comparator | Propofol | Small molecule | 60 mg | Intravenous |
| Comparator | pethidin hydrochlorid | Unknown | 25 mg | Intravenous |