drugset / Trial / NCT01568255

Is Treatment of Vitamin D Deficiency Associated With Resolution of Statin-Induced Muscular Symptoms

NCT01568255

Phase 4 Completed 11 enrolled Cedars-Sinai Medical Center
RandomizedParallel-groupDouble-blindTreatment

Summary

Statins are a class of drugs that are highly effective at lowering cholesterol levels. However, compliance is often limited by symptoms of muscle pain. The investigators would like to study Vitamin-D deficient individuals who also have muscle pain due to statin use. About 1 billion people are estimated to have low or insufficient levels of vitamin D worldwide. Patients with low or insufficient levels of vitamin D may develop muscle disease. The purpose of this study is to identify if these symptoms are associated with vitamin D deficiency, and most importantly, if treatment of vitamin D deficiency can reduce muscle pain that is caused by statin treatment.

Timeline

Start
2012-03
Primary completion
2019-06
Completion
2019-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Ergocalciferol Small molecule 50000 iu

Indications