drugset / Trial / NCT01570296
A Trial of Gefitinib in Combination With BKM120 in Patients With Advanced Non-Small Cell Lung Cancer, With Enrichment for Patients Whose Tumours Harbour Molecular Alterations of PI3K Pathway and Known to Overexpress EGFR
NaSingle-groupOpen-labelTreatment
Summary
The safety, tolerability and recommended phase 2 dose (RP2D) of the combination of gefitinib and BKM120 will be determined.
Timeline
- Start
- 2011-10-03
- Primary completion
- 2016-02-22
- Completion
- 2018-12-17
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Buparlisib | Small molecule | — | Oral |
| Subject | Gefitinib | Small molecule | — | — |