drugset / Trial / NCT01570296

A Trial of Gefitinib in Combination With BKM120 in Patients With Advanced Non-Small Cell Lung Cancer, With Enrichment for Patients Whose Tumours Harbour Molecular Alterations of PI3K Pathway and Known to Overexpress EGFR

NCT01570296

NaSingle-groupOpen-labelTreatment

Summary

The safety, tolerability and recommended phase 2 dose (RP2D) of the combination of gefitinib and BKM120 will be determined.

Timeline

Start
2011-10-03
Primary completion
2016-02-22
Completion
2018-12-17

Drugs

EvaluationDrugModalityDoseRoute
Subject Buparlisib Small molecule Oral
Subject Gefitinib Small molecule