drugset / Trial / NCT01570608
Lucentis KAV Study
Phase 3
Completed
51 enrolled
The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
RandomizedParallel-groupSingle-blindTreatment
Summary
Ranibizumab has been proven to be effective in large multicentre studies. However, the injections have to be repeated monthly. A combined therapy with the established photodynamic therapy might even be more effective, less intravitreal injections might be necessary due to a synergistic effect. The study will be conducted to explore whether intravitreal ranibizumab in monotherapy or in combination with verteporfin photodynamic therapy under a new time regime is an effective, safe and convenient treatment for patients with subfoveal Choroidal Neovascularisation (CNV) secondary to Age-Related Macular Degeneration (AMD).
Timeline
- Start
- 2007-03
- Primary completion
- 2011-08
- Completion
- 2011-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ranibizumab | Monoclonal antibody | — | Intravitreal |
| Comparator | Verteporfin | Other / unclassified | — | — |