A 2-part Study to Assess Local Tolerability, Safety and Pharmacokinetics of Ceftaroline in Healthy Subjects

Phase 1 Completed 34 enrolled Pfizer

RandomizedCrossoverTriple-blindBasic science

Summary

The purpose of this study is to assess the safety, tolerability, and pharmacokinetics of Ceftaroline 600 mg when administered by varying infusion volumes.

Timeline

Start: 2012-04
Primary completion: 2012-09
Completion: 2012-09

Publications

Edeki T, Kujacic M, Broadhurst H, Li J, Sunzel M. Safety, local tolerability and pharmacokinetics of ceftaroline fosamil administered in a reduced infusion volume. Br J Clin Pharmacol. 2014 Dec;78(6):1291-7. doi: 10.1111/bcp.12465.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ceftaroline	Other / unclassified	600 mg	Intravenous

Indications

No indication recorded.