B-type Natriuretic Peptide as a Surrogate Marker Guiding Post-operative Fluid Off-loading

Summary

The long-range goal of this proposal is to decrease morbidity and mortality related to pulmonary edema and congestive heart failure (CHF) in post-operative patients. The short-range goal is to determine a mechanistic endpoint when therapy for impending heart failure can be initiated and terminated based on B-type natriuretic peptide (BNP) levels. The investigators propose to utilize changing levels of BNP as a surrogate marker for CHF.

Timeline

Start

2012-07

Primary completion

2013-06

Completion

2013-06

Drugs

Indications

No indication recorded.