Efavirenz Versus Rilpivirine on Vascular Function, Inflammation, and Oxidative Stress

Summary

The purpose of this study is to compare the cardiovascular profiles of efavirenz and rilpivirine, which are two drugs used to treat HIV infection.

Timeline

Start

2012-07

Primary completion

2014-05

Completion

2014-11

Publications

• Gupta SK, Slaven JE, Kamendulis LM, Liu Z. A randomized, controlled trial of the effect of rilpivirine versus efavirenz on cardiovascular risk in healthy volunteers. J Antimicrob Chemother. 2015 Oct;70(10):2889-93. doi: 10.1093/jac/dkv195. Epub 2015 Jul 13.

Drugs

Indications