drugset / Trial / NCT01586325

A Study of the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of JNJ-47910382 at Different Doses and Dose Regimens in Asian Genotype-1, Chronic, HCV-Infected Patients

NCT01586325 ↗

Phase 1 Terminated 8 enrolled Janssen R&D Ireland
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to determine the safety, tolerability, pharmacokinetics (how a drug is absorbed and distributed in the body), and intrinsic antiviral activity of JNJ-47910382 after 5 consecutive days of administration in chronic, hepatitis C virus (HCV)-genotype-1-infected patients at different doses and dose regimens.

Timeline

Start
2012-05-25
Primary completion
2014-04-21
Completion
2014-04-21

Outcome

Outcome not reported

Stopped: “Because of many competing trials using the same mechanism of action, but being further advanced in development”

Drugs

EvaluationDrugModalityDoseRoute
Subject JNJ-47910382 Unknown 30 mg Oral
Subject JNJ-47910382 Unknown 90 mg Oral
Subject JNJ-47910382 Unknown 200 mg Oral