drugset / Trial / NCT01587651

Pharmacodynamic Evaluation of Switching From Ticagrelor to Prasugrel in Subjects With Stable Coronary Artery Disease

NCT01587651

Phase 4 Completed 110 enrolled Daiichi Sankyo Eli Lilly and Company · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a Phase 4, multicenter, open-label (blinded Pharmacodynamic PD results), randomized, 3-arm, parallel-design study of subjects with stable Coronary Artery Disease CAD. This study will compare the PD effect of prasugrel 10 mg QD (once-daily) maintenance dose with ticagrelor 90 mg BID (twice daily) maintenance dose in subjects with stable CAD who have previously received ticagrelor loading does (LD) and maintenance dose (MD)..

Timeline

Start
2012-03
Primary completion
2013-02
Completion
2013-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Prasugrel Small molecule 10 mg
Comparator Ticagrelor Small molecule 90 mg