drugset / Trial / NCT01588509
Transition From Alendronate to Romosozumab (AMG 785)
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to estimate the percent change from baseline in lumbar spine bone mineral density (BMD) following multiple-dose administrations of romosozumab in postmenopausal women with low BMD previously treated with alendronate.
Timeline
- Start
- 2012-03-30
- Primary completion
- 2012-11-21
- Completion
- 2012-11-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Romosozumab | Monoclonal antibody | 140 mg | Subcutaneous |
| Subject | Romosozumab | Monoclonal antibody | 210 mg | Subcutaneous |