drugset / Trial / NCT01590108
The Study of Apelin-APJ System on Pulmonary Hypertension Patients and Healthy Subjects
RandomizedCrossoverDouble-blindTreatment
Summary
The purpose of this study is to * Determine blood peptide levels and investigate any tissue gradients of apelin in patients with idiopathic pulmonary arterial hypertension and healthy volunteers. * Evaluate the effect of exogenous apelin infusion on exercise performance in healthy volunteers and patients with idiopathic pulmonary arterial hypertension.
Timeline
- Start
- 2012-03
- Primary completion
- 2014-09
- Completion
- 2014-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | (Pyr1)apelin-13 | Unknown | 30 unknown | Intravenous |