drugset / Trial / NCT01590108

The Study of Apelin-APJ System on Pulmonary Hypertension Patients and Healthy Subjects

NCT01590108 ↗

Phase 1 Completed 12 enrolled Imperial College London
RandomizedCrossoverDouble-blindTreatment

Summary

The purpose of this study is to * Determine blood peptide levels and investigate any tissue gradients of apelin in patients with idiopathic pulmonary arterial hypertension and healthy volunteers. * Evaluate the effect of exogenous apelin infusion on exercise performance in healthy volunteers and patients with idiopathic pulmonary arterial hypertension.

Timeline

Start
2012-03
Primary completion
2014-09
Completion
2014-09

Drugs

EvaluationDrugModalityDoseRoute
Subject (Pyr1)apelin-13 Unknown 30 unknown Intravenous