drugset / Trial / NCT01590277

Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans

NCT01590277

Phase 1 Completed 33 enrolled VA Office of Research and Development
RandomizedCrossoverQuadruple-blindBasic science

Summary

Alcohol is abused commonly, but there is no remedy for alcohol intoxication. This project is looking at the substance iomazenil and its effect on alcohol intoxication and alcohol's effects on driving using a driving simulator.

Timeline

Start
2012-12-14
Primary completion
2018-11-02
Completion
2018-11-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Alcohol Other / unclassified 0.1 %
Subject Iomazenil Small molecule 3.7 ug/kg Intravenous