drugset / Trial / NCT01590875

Validation Durability Adenosine Effect in Verification Pulmonary Vein Isolation

NCT01590875

Completed 20 enrolled Medical College of Wisconsin
RandomizedParallel-groupOpen-labelDiagnostic

Summary

Adenosine is used clinically to assess permanency of electrical isolation of pulmonary veins during atrial fibrillation ablation, however, the methodology has not been validated either in terms of the reproducibility of the adenosine response or the effect on clinical outcomes, namely whether using pulmonary vein reconnection to guide additional ablation lowers rate recurrent atrial fibrillation post ablation. Study will test the hypothesis that the response to adenosine used in this manner is reproducible over time.

Timeline

Start
2012-05
Primary completion
2015-06
Completion
2015-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Adenosine Small molecule 12 mg Intravenous

Indications