drugset / Trial / NCT01590875
Validation Durability Adenosine Effect in Verification Pulmonary Vein Isolation
RandomizedParallel-groupOpen-labelDiagnostic
Summary
Adenosine is used clinically to assess permanency of electrical isolation of pulmonary veins during atrial fibrillation ablation, however, the methodology has not been validated either in terms of the reproducibility of the adenosine response or the effect on clinical outcomes, namely whether using pulmonary vein reconnection to guide additional ablation lowers rate recurrent atrial fibrillation post ablation. Study will test the hypothesis that the response to adenosine used in this manner is reproducible over time.
Timeline
- Start
- 2012-05
- Primary completion
- 2015-06
- Completion
- 2015-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Adenosine | Small molecule | 12 mg | Intravenous |