Proactive Treatment of Tacrolimus Ointment for Adult Facial Seborrheic Dermatitis

Phase 4 Completed 104 enrolled Pusan National University Hospital

RandomizedCrossoverDouble-blindTreatment

Summary

The purpose of this study is to determine whether proactive use of 0.1% tacrolimus ointment once or twice weekly can keep adult facial SD in remission and reduce the incidence of exacerbation.

Timeline

Start: 2010-11
Primary completion: 2011-05
Completion: 2011-05

Outcome

Met primary endpoint

paper In conclusion, twice-weekly treatment with 0.1% tacrolimus ointment had superior effects in keeping facial seborrhoeic dermatitis in remission. PMID 23388687 ↗

Publications

Kim TW, Mun JH, Jwa SW, Song M, Kim HS, Ko HC, Kim MB, Song KH, Lee SK, Seo JK, Lee D, Kim BS. Proactive treatment of adult facial seborrhoeic dermatitis with 0.1% tacrolimus ointment: randomized, double-blind, vehicle-controlled, multi-centre trial. Acta Derm Venereol. 2013 Sep 4;93(5):557-61. doi: 10.2340/00015555-1532.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Tacrolimus	Small molecule	0.1 %	Topical