drugset / Trial / NCT01591629
The Effects of ∆-9-THC and Naloxone in Humans
RandomizedCrossoverQuadruple-blindBasic science
Summary
The purpose of this project is to examine the effects of mu-opiate antagonism on the rewarding and reinforcing effects of delta-9-tetrahydrocannabinol (THC), the main psychoactive ingredient of cannabis.
Timeline
- Start
- 2011-11-04
- Primary completion
- 2012-06-01
- Completion
- 2012-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dronabinol | Other / unclassified | 0.025 mg/kg | Intravenous |
| Subject | Naloxone | Small molecule | 18 ug/kg | Intravenous |
| Subject | Naloxone | Small molecule | 1 mg | Intravenous |
| Subject | Naloxone | Small molecule | 2 mg | Intravenous |
Indications
No indication recorded.