Local Metabolic Effects of Ghrelin in Skeletal Muscle and Adipose Tissue

Phase 0 Completed 10 enrolled Esben Thyssen Vestergaard

RandomizedCrossoverSingle-blindBasic science

Summary

The metabolic effects of ghrelin is investigated by microdialysis technique. Subjects are healthy young men. End points are interstitial concentrations of glucose, lactate, and glycerol.

Timeline

Start: 2012-06
Primary completion: 2012-09
Completion: 2013-01

Publications

Vestergaard ET, Moller N, Jorgensen JO. Acute peripheral tissue effects of ghrelin on interstitial levels of glucose, glycerol, and lactate: a microdialysis study in healthy human subjects. Am J Physiol Endocrinol Metab. 2013 Jun 15;304(12):E1273-80. doi: 10.1152/ajpendo.00662.2012. Epub 2013 Apr 16.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ghrelin	Peptide	0.0125 ng	Other

Indications

No indication recorded.