drugset / Trial / NCT01596868

GP VS TP in the Treatment of Advanced Nasopharyngeal Carcinoma in Northwest China

NCT01596868 ↗

Phase 2 Completed 60 enrolled Air Force Military Medical University, China
RandomizedParallel-groupOpen-labelTreatment

Summary

The present study is a randomized, control, phase II study of locally advanced nasopharyngeal carcinoma (NPC) in Northwest China treated with Gemcitabine plus cisplatin regimen (GP) or Docetaxel plus cisplatin regimen (TP) induction chemotherapy followed by concurrent chemoradiotherapy. The population consists of stage III-IVb nasopharyngeal carcinoma (NPC). The effectiveness, side effects and quality of life will be evaluated according to Standard WHO response criteria, NCI-CTC AE V3.0 and EORTC QLQ-C30 and H\&N35 questionnaire.

Timeline

Start
2012-05
Primary completion
2013-10
Completion
2013-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Docetaxel Small molecule 75 mg/m2 —
Comparator Gemcitabine Small molecule 1000 mg/m2 Intravenous
Comparator Cisplatin Other / unclassified 80 mg/m2 Intravenous