drugset / Trial / NCT01598363
An Open-Label Study of the Effect of Bardoxolone Methyl on the Single Dose Pharmacokinetics of Digoxin and Rosuvastatin in Healthy Volunteers
RandomizedParallel-groupOpen-labelBasic science
Summary
The purpose of this study is to evaluate the potential effect of bardoxolone methyl on the pharmacokinetics of digoxin and rosuvastatin and to assess the safety of the concomitant administration of bardoxolone methyl with digoxin or rosuvastatin.
Timeline
- Start
- 2012-06-30
- Primary completion
- 2012-07-31
- Completion
- 2012-07-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Digoxin | Other / unclassified | 0.5 mg | Oral |
| Subject | Rosuvastatin | Small molecule | 20 mg | Oral |
Indications
No indication recorded.