drugset / Trial / NCT01598402

Efficacy of Prophylactic Treatment With Antibiotics During Concomitant Chemoradiotherapy in Patients With Head and Neck Cancer to Prevent Aspiration Pneumonia

NCT01598402 ↗

Phase 2/3 Unknown 106 enrolled Radboud University Medical Center
RandomizedParallel-groupOpen-labelTreatment

Summary

Patients with locally advanced head and neck cancer treated with chemo-radiotherapy have (during and shortly after this treatment) a high risk of developing pneumonia by aspiration. This pneumonia is often associated with a hospital admission and affects the quality of life. The purpose of the study, is to determine whether prophylactic antibiotics may decrease the development of pneumonia. Prophylactic antibiotics means that there are no signs of pneumonia are already

Timeline

Start
2011-12
Primary completion
2013-12
Completion
2014-12

Drugs

EvaluationDrugModalityDoseRoute
Subject amoxicillin/clavulanic acid Unknown 625 mg —

Indications