drugset / Trial / NCT01600521

A Clinical Study of a Natural Remedy for Rheumatoid Arthritis vs. Commonly Used Conventional Medications

NCT01600521

Completed 1748 enrolled University of Minnesota
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to evaluate the efficacy and safety of a combined therapy for rheumatoid arthritis (RA). The combined therapy contained paeoniflorin (Brand name: Pafulin), which has anti-inflammation properties, and Cervus and Cucumis polypeptide injection (Brand name: Songmeile), which has bone healing, pain relieving, and anti-inflammation properties. The hypothesis is that this remedy, which has long been used by the world's largest RA community, is effective and safe when tested by modern clinical standards and criteria.

Timeline

Start
2004-11
Primary completion
2011-04
Completion
2012-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator A Natural Remedy for Rheumatoid Arthritis vs. Common Drugs Unknown 8 ml Intravenous
Comparator A Natural Remedy for Rheumatoid Arthritis vs. Common Drugs Unknown 12 ml Intravenous
Comparator Leflunomide Small molecule 10 mg Oral
Comparator Leflunomide Small molecule 20 mg Oral
Comparator Methotrexate Small molecule 7.5 mg Oral
Comparator Methotrexate Small molecule 10 mg Oral
Comparator Paeoniflorin Small molecule 600 mg Oral

Indications