drugset / Trial / NCT01602900
Healthy Volunteer Positron Emission Tomography (PET) Brain Occupancy Study of a Phosphodiesterase 4 (PDE4) Inhibitor in Huntington's Disease
Non-randomizedSingle-groupOpen-labelTreatment
Summary
This study will investigate if a new experimental drug to treat Huntington's Disease gets into the brain. If it does get into the brain the study will explore the relationship between the amount of drug in the brain and the amount of drug in the blood. The study will involve healthy male volunteers.
Timeline
- Start
- 2011-11-22
- Primary completion
- 2012-04-12
- Completion
- 2012-04-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | GSK356278 | Small molecule | — | Oral |
| Background | Rolipram | Diagnostic / imaging agent | — | — |