drugset / Trial / NCT01603121

Lisofylline as Continuous Subcutaneous and Intravenous Administration in Subjects With Type 1 Diabetes Mellitus

NCT01603121

Phase 1/2 Terminated 1 enrolled Eastern Virginia Medical School
RandomizedCrossoverOpen-labelBasic science

Summary

The primary goal of the study is to investigate the safety and tolerability of the investigational drug lisofylline, when administered under the skin or in the vein, in people with type 1 diabetes. A second aim is to determine how much drug is available in the blood after injection under the skin, compared to injection in the vein.

Timeline

Start
2012-02
Primary completion
2013-05
Completion
2013-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Lisofylline Small molecule 9 mg/kg Subcutaneous
Subject Lisofylline Small molecule 12 mg/kg Subcutaneous