drugset / Trial / NCT01603121
Lisofylline as Continuous Subcutaneous and Intravenous Administration in Subjects With Type 1 Diabetes Mellitus
RandomizedCrossoverOpen-labelBasic science
Summary
The primary goal of the study is to investigate the safety and tolerability of the investigational drug lisofylline, when administered under the skin or in the vein, in people with type 1 diabetes. A second aim is to determine how much drug is available in the blood after injection under the skin, compared to injection in the vein.
Timeline
- Start
- 2012-02
- Primary completion
- 2013-05
- Completion
- 2013-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lisofylline | Small molecule | 9 mg/kg | Subcutaneous |
| Subject | Lisofylline | Small molecule | 12 mg/kg | Subcutaneous |