A Study of Cannabis Based Medicine Extracts and Placebo in Patients With Pain Due to Spinal Cord Injury

Phase 3 Completed 116 enrolled Jazz Pharmaceuticals

RandomizedParallel-groupQuadruple-blindTreatment

Summary

A study to investigate the effects of sublingual cannabis based medicine extracts on neuropathic pain associated with spinal cord injury.

Timeline

Start: 2002-07
Primary completion: 2005-01
Completion: 2005-01

Outcome

Missed primary endpoint

registry analysis (unspecified test); GW-1000-02 vs Placebo; p = 0.708; Estimated mean treatment difference -0.08 (95% CI -0.51 to 0.35); ANCOVA NCT01606202 ↗

Publications

Thomas PA, Carter GT, Bombardier CH. A scoping review on the effect of cannabis on pain intensity in people with spinal cord injury. J Spinal Cord Med. 2022 Sep;45(5):656-667. doi: 10.1080/10790268.2020.1865709. Epub 2021 Jan 19.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Nabiximols	Other / unclassified	2.5 mg	Other
Subject	Nabiximols	Other / unclassified	2.7 mg	Other

Indications

No indication recorded.