Comparison of Body Weight Change During Contraception With Belara and Yasmin

Phase 4 Unknown 100 enrolled Mahidol University

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to evaluate different side effect in contraceptive use of two oral combined contraceptive pills (OCP)in combination of 30 mcg ethinylestradiol/2 mg chlormadinone acetate (Belara®) and 30 mcg ethinylestradiol/3 mg drospirenone (Yasmin®), especially body weight change.

Timeline

Start: 2012-06
Primary completion: 2016-01
Completion: 2016-02

Publications

Wongwananuruk T, Panichyawat N, Panchalee T, Jirakittidul P, Angsuwathana S, Sirimai K, Thamkhantho M, Chiravacharadej G. Comparison of change in body weight between contraception containing 30-mug ethinylestradiol/2-mg chlormadinone acetate or 30-mug ethinylestradiol/3-mg drospirenone: a randomised controlled trial. Eur J Contracept Reprod Health Care. 2020 Feb;25(1):43-48. doi: 10.1080/13625187.2019.1688290. Epub 2019 Nov 22.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	chlormadinone acetate	Small molecule	2 mg	Oral
Subject	drospirenone	Unknown	3 mg	Oral
Subject	ethinyl estradiol	Small molecule	30 ug	Oral

Indications

No indication recorded.