Human Rabies Immunoglobulin (HRIG)- Dosage Determination and Interference With the Active Immune Response

Summary

Dosage of rabies immune globulin was calculated from the victim's body weight, then the amount of rabies immune globulin would be injected as much as possible to all of the wounds. Increase dosage of rabies immune globulin was needed in situation of multiple severe bite-wounds especially among children whose had lower body weight than adults. Our study would be conducted in order to determine whether the increase dosage of rabies immune globulin would interfere with the protective antibody levels against rabies.

Timeline

Start

2012-06

Primary completion

2018-04

Completion

2018-04

Drugs

Indications