A Study of TAS-114 in Combination With S-1 in Patients With Advanced Solid Tumors

Summary

This is a phase 1 study of TAS-114 in combination with S-1 in patients with advanced solid tumors.

Timeline

Start

2012-06

Primary completion

2017-02

Completion

2017-02

Publications

• Doi T, Yoh K, Shitara K, Takahashi H, Ueno M, Kobayashi S, Morimoto M, Okusaka T, Ueno H, Morizane C, Okano N, Nagashima F, Furuse J. First-in-human phase 1 study of novel dUTPase inhibitor TAS-114 in combination with S-1 in Japanese patients with advanced solid tumors. Invest New Drugs. 2019 Jun;37(3):507-518. doi: 10.1007/s10637-018-0697-3. Epub 2018 Dec 4.

Drugs

Indications