Shensong Yangxin Capsule in the Treatment of Heart Failure Complicated With Ventricular Premature Beat

Phase 4 Unknown 460 enrolled Cong-xin Huang Chinese Academy of Medical Sciences, Fuwai Hospital · collab Fudan University · collab Nanjing Medical University · collab Shanghai Changzheng Hospital · collab Third Military Medical University · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to assess the effects of Chinese medicine Shensong Yangxin capsule for the chronic cardiac dysfunction complicated with ventricular premature beats.

Timeline

Start: 2012-09
Primary completion: 2013-08
Completion: 2013-12

Outcome

Met primary endpoint

paper SSYX caused a significantly greater decline in the total number of VPCs than the placebo did PMID 28685712 ↗

paper (-2145 ± 2848 vs. -841 ± 3411, P < 0.05). PMID 28685712 ↗

Publications

Wang X, Hu D, Dang S, Huang H, Huang CX, Yuan MJ, Tang YH, Zheng QS, Yin F, Zhang S, Zhang BL, Gao RL; Efficacy and Safety of Shensong Yangxin Capsules for Frequent VPCs in Congestive Heart Failure Study Group. Effects of Traditional Chinese Medicine Shensong Yangxin Capsules on Heart Rhythm and Function in Congestive Heart Failure Patients with Frequent Ventricular Premature Complexes: A Randomized, Double-blind, Multicenter Clinical Trial. Chin Med J (Engl). 2017 Jul 20;130(14):1639-1647. doi: 10.4103/0366-6999.209906.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Shensong Yangxin capsule	Traditional medicine (herbal / TCM)	4 unknown	Oral