drugset / Trial / NCT01613703

ONO-2952 Single-dose PET Study in Healthy Adult Subjects

NCT01613703 ↗

NaSingle-groupOpen-labelTreatment

Summary

The primary objective of this study is to evaluate the brain TSPO occupancy of ONO-2952 in healthy adult subjects after a single dose using \[11C\]PBR28 as a specific PET ligand for TSPO. The secondary objective is to evaluate the relationship between TSPO occupancy and the plasma concentration of ONO-2952 and to investigate the safety and tolerability of ONO-2952 in healthy subjects.

Timeline

Start
2012-08
Primary completion
2013-03
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject ONO-2952 Small molecule 1 mg —
Subject ONO-2952 Small molecule 200 mg —

Indications

No indication recorded.