drugset / Trial / NCT01613703
ONO-2952 Single-dose PET Study in Healthy Adult Subjects
NaSingle-groupOpen-labelTreatment
Summary
The primary objective of this study is to evaluate the brain TSPO occupancy of ONO-2952 in healthy adult subjects after a single dose using \[11C\]PBR28 as a specific PET ligand for TSPO. The secondary objective is to evaluate the relationship between TSPO occupancy and the plasma concentration of ONO-2952 and to investigate the safety and tolerability of ONO-2952 in healthy subjects.
Timeline
- Start
- 2012-08
- Primary completion
- 2013-03
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ONO-2952 | Small molecule | 1 mg | — |
| Subject | ONO-2952 | Small molecule | 200 mg | — |
Indications
No indication recorded.