drugset / Trial / NCT01614795

Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma

NCT01614795

Phase 2 Completed 46 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies how well cixutumumab and temsirolimus work in treating patients with recurrent or refractory sarcoma. Monoclonal antibodies, such as cixutumumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Temsirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving cixutumumab and temsirolimus together may kill more tumor cells.

Timeline

Start
2012-06-18
Primary completion
2014-04-01
Completion
2014-04-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cixutumumab Monoclonal antibody Intravenous
Subject Temsirolimus Small molecule Intravenous