drugset / Trial / NCT01619176
Acupuncture Study on Rheumatoid Arthritis, Monitoring Microbiome and Blood
Completed
10 enrolled
Chinese Academy of Sciences
Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine · collab
Non-randomizedSingle-groupOpen-labelBasic science
Summary
Acupuncture is used and recommended by the WHO for the treatment of Rheumatoid Arthritis. The molecular bases of this recommendation are not known, the investigators want to compare with the usage of high-throughput molecular technologies the variations occurring in patients treated with acupuncture and conventional treatment with the ones treated with conventional treatment only. The investigators observe the variations in blood and in the gut microbiome.
Timeline
- Start
- 2012-10
- Primary completion
- 2014-12
- Completion
- 2014-12
Publications
- Results Liu, Y. et al. (2023). Wound Healing from Bench to Bedside: A PPPM Bridge Between Physical Therapies and Chronic Inflammation. In: Podbielska, H., Kapalla, M. (eds) Predictive, Preventive, and Personalised Medicine: From Bench to Bedside. Advances in Predictive, Preventive and Personalised Medicine, vol 17. Springer, Cham. https://doi.org/10.1007/978-3-031-34884-6_12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Leflunomide | Small molecule | 20 mg | — |
| Background | Methotrexate | Small molecule | 7.5 mg | — |
| Background | Methotrexate | Small molecule | 15 mg | — |