drugset / Trial / NCT01620268
An Open-Label, Study to Treat Patients With Renal Allograft and Polyoma BK Viruria
RandomizedParallel-groupOpen-labelPrevention
Summary
This study will evaluate the clinical efficacy and safety of a combination of leflunomide and orotic acid in kidney transplant patients with high levels of Polyoma BK viruria for the purpose of preventing Polyoma BK viremia and Nephropathy that could lead to kidney transplant loss from viral damage, acute rejection or both.
Timeline
- Start
- 2012-07
- Primary completion
- 2018-06
- Completion
- 2018-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Leflunomide | Small molecule | — | — |
| Subject | Orotic acid | Small molecule | 600 mg | — |
Indications
No indication recorded.