drugset / Trial / NCT01621022
Bupropion Alone or Combined With Nicotine Gum
Phase 4
Completed
608 enrolled
University of Wisconsin, Madison
National Institutes of Health (NIH) · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
Focus of this study was to determine if bupropion was more effective for smoking cessation when used alone or combined with nicotine gum.
Timeline
- Start
- 2001-01
- Primary completion
- 2002-10
- Completion
- 2002-10
Publications
- Results Piper ME, Federman EB, McCarthy DE, Bolt DM, Smith SS, Fiore MC, Baker TB. Efficacy of bupropion alone and in combination with nicotine gum. Nicotine Tob Res. 2007 Sep;9(9):947-54. doi: 10.1080/14622200701540820.
- Hajizadeh A, Howes S, Theodoulou A, Klemperer E, Hartmann-Boyce J, Livingstone-Banks J, Lindson N. Antidepressants for smoking cessation. Cochrane Database Syst Rev. 2023 May 24;5(5):CD000031. doi: 10.1002/14651858.CD000031.pub6.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupropion | Small molecule | 150 mg | — |
| Comparator | Nicotine | Unknown | 4 mg | — |