drugset / Trial / NCT01621620

The Role of Sympatho-vagal Balance on Different Limbs of Pain Perception in Healthy Subjects

NCT01621620

Unknown 20 enrolled Tel-Aviv Sourasky Medical Center
NaSingle-groupOpen-labelBasic science

Summary

objectives 1. To study the sympatho-vagal balance effect on different limbs of pain perception. 2. To determine whether it is the hypertension by itself or the baroreflex activation due to blood pressure rise that is responsible for the analgesic effect of acute hypertension. study questions The study questions are derived from the study objectives: 1. Does sympatho-vagal balance influence pain perception? 2. Does sympatho-vagal balance influence diffuse noxious inhibitory control systems? 3. Does sympatho-vagal balance influence temporal summation? 4. Does the hypoalgesic effect to acute increase in blood pressure a result of baroreflex activation?

Timeline

Start
2012-08
Primary completion
2013-08
Completion
2014-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Yohimbine Small molecule

Indications

No indication recorded.