drugset / Trial / NCT01624857

Statin for Depression in Patients Undergoing Coronary Artery Bypass Graft

NCT01624857

RandomizedParallel-groupTriple-blindPrevention

Summary

Depression is frequently observed in patients with coronary heart disease (CHD) and represents a significant risk factor for major cardiovascular events. Previous study has proved that high sensitive C-reactive protein (hsCRP) was an independent predictor for depression in CABG patients at 6 months after bypass surgery. Statins can effectively reduce the blood levels of hsCRP. This study aim to examine whether statins can improve the prognosis of depressive patients undergoing coronary artery bypass surgery through reducing the levels of hsCRP.

Timeline

Start
2012-06
Primary completion
2013-12
Completion
2014-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Rosuvastatin Small molecule 20 mg