drugset / Trial / NCT01625442

Crocus Sativus (Saffron) and Berberis Vulgaris (Barberry Fruit) in Metabolic Syndrome

NCT01625442

Phase 4 Completed 732 enrolled Birjand University of Medical Sciences
RandomizedParallel-groupSingle-blindTreatment

Summary

The metabolic syndrome is associated with increased risk of cardiovascular disease and diabetes mellitus. The age-adjusted prevalence of the metabolic syndrome in the United States is 34% for men and 35% for women. Emerging alternative medicine worldwide led investigators to evaluate the efficacy of Crocus sativus (Saffron) and Berberis Vulgaris (barberry fruit) in treatment of metabolic syndrome. Serum total cholesterol, serum LDL cholesterol, serum HDL cholesterol, serum triglyceride, Fasting Blood Sugar and hematocrit measured before and after 45 days of treatment.

Timeline

Start
2010-01
Primary completion
2011-07
Completion
2012-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Barberry Traditional medicine (herbal / TCM) 200 mg
Comparator Saffron Traditional medicine (herbal / TCM) 100 mg