drugset / Trial / NCT01625806

A Study of The Effects of Multiple Doses of Ketoconazole on Single Dose Pharmacokinetics of RO4602522 in Healthy Male Volunteers

NCT01625806

Phase 1 Completed 34 enrolled Hoffmann-La Roche
Non-randomizedParallel-groupOpen-label

Summary

This single-center, open-label, parallel group study will evaluate the effects of multiple doses of ketoconazole on the pharmacokinetics of single oral dose RO4602522 in healthy male volunteers. All subjects will receive a single oral dose of RO4602522 on Day 1. Subjects assigned to Group 2 will additionally receive ketoconazole (200 mg orally every 12 hours) from Day 1 to Day 17.

Timeline

Start
2012-07
Primary completion
2012-12
Completion
2012-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketoconazole Small molecule 200 mg Oral
Subject RO4602522 Unknown Oral

Indications

No indication recorded.