drugset / Trial / NCT01625936

CRLX101 Plus Bevacizumab in Advanced RCC

NCT01625936

Phase 1 Completed 22 enrolled Abramson Cancer Center at Penn Medicine
NaSingle-groupTreatment

Summary

This is a Phase 1b, dose escalation study of the investigational agent, CRLX101, given in combination with Bevacizumab in patients with advanced renal cell carcinoma. The purpose of this study is to determine the initial safety and effectiveness of this agent in combination with Bevacizumab. The investigators are also trying to determine the best dose level of CRLX101 to give in combination with bevacizumab. About 22 subjects will be enrolled in this study at the University of Pennsylvania.

Timeline

Start
2012-06
Primary completion
2017-07-01
Completion
2018-07-16

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody
Subject DAVAMOTECAN PEGADEXAMER Other / unclassified

Indications