drugset / Trial / NCT01626560
The Effects of Daptomycin and Cytokines Production in Comparison With Vancomycin
RandomizedSingle-groupOpen-labelBasic science
Summary
Primary: To determine the influence of daptomycin on inflammatory cytokine (IL-1, TNF and IL-6) for the treatment of complicated cellulitis/erysipela compared with alternative treatment (vancomycin or oxacillin). Secondary: To evaluate the clinical outcome of both groups according to levels of the cytokines evaluated.
Timeline
- Start
- 2012-07
- Primary completion
- 2015-03
- Completion
- 2015-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Daptomycin | Other / unclassified | 4 mg/kg | — |
| Subject | Daptomycin | Other / unclassified | 6 mg/kg | — |
| Subject | Vancomycin | Other / unclassified | 1 g | — |