drugset / Trial / NCT01628042

A Single Dose Study of the Pharmacokinetics of Vibegron (MK-4618) in Participants With Renal Insufficiency (MK-4618-014)

NCT01628042

Phase 1 Completed 32 enrolled Merck Sharp & Dohme LLC
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This study will investigate the impact of impaired renal function on the plasma pharmacokinetics of vibegron (MK-4618) to guide use of vibegron in clinical trials in participants with overactive bladder and to guide recommendations on potential dosing adjustments for individuals with varying degrees of renal impairment.

Timeline

Start
2012-07-16
Primary completion
2013-01-25
Completion
2013-01-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Vibegron Unknown 100 mg Oral

Indications