drugset / Trial / NCT01630733

A Multinational, Randomized, Open-Label Study of Custirsen In Patients With Advanced or Metastatic (Stage IV) Non-Small Cell Lung Cancer

NCT01630733

Phase 3 Completed 664 enrolled Achieve Life Sciences
RandomizedParallel-groupOpen-labelTreatment

Summary

The primary objective of the study is to compare overall survival of participants randomized to receiving custirsen in combination with docetaxel with participants randomized to receive docetaxel alone.

Timeline

Start
2012-10-24
Primary completion
2016-11-17
Completion
2016-11-17

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule 75 mg/m2 Intravenous
Subject custirsen Antisense oligonucleotide 640 mg Intravenous