Effect of the Aquaretic Tolvaptan on Nitric Oxide System (TORA)

Summary

The purpose of this study is to investigate the effect of tolvaptan on renal water, sodium and potassium excretion, plasma concentration of vasoactive hormones,central blood pressure, pulse wave velocity (PWV) and augmentation index, basal and during inhibition of nitric oxide synthesis in healthy subjects.

Timeline

Start

2012-05

Primary completion

2014-03

Completion

2014-03

Drugs

Indications