A Randomized, Multi-Center Biomarker Trial to Predict Therapeutic Responses of Patients With Rheumatoid Arthritis to a Specific Biologic Mode of Action

Summary

The purpose of this study is to find biological response patterns of patients with rheumatoid arthritis to drugs with different biologic modes of action. This study should help to predict therapeutic responses and to find the right therapy for the right patient.

Timeline

Start

2012-05

Primary completion

2018-08-01

Completion

2018-08-01

Publications

• Studenic P, Bond G, Kerschbaumer A, Becede M, Pavelka K, Karateev D, Stieger J, Puchner R, Mueller RB, Puchhammer-Stockl E, Durechova M, Loiskandl M, Perkmann T, Olejarova M, Luchikhina E, Steiner CW, Bonelli M, Smolen JS, Aletaha D. Torque Teno Virus quantification for monitoring of immunomodulation with biologic compounds in the treatment of rheumatoid arthritis. Rheumatology (Oxford). 2022 Jul 6;61(7):2815-2825. doi: 10.1093/rheumatology/keab839.

Drugs

Indications