drugset / Trial / NCT01641510

PRAsugrel or clopIdogrel In Acute Coronary SyndromE With CYP2C19 GENEtic Variants

NCT01641510

Phase 3 Completed 70 enrolled Dong-A University
RandomizedParallel-groupSingle-blindPrevention

Summary

The investigators hypothesize that reduced loading dose of prasugrel followed by reduced maintenance dose of prasugrel in acute coronary syndrome patients with CYP2C19 polymorphism undergoing percutaneous coronary intervention might exhibit lower platelet reactivity 24 hours and 30 days later which is associated with major adverse cardiovascular events.

Timeline

Start
2013-10
Primary completion
2018-10
Completion
2019-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Clopidogrel Small molecule 75 mg
Subject Prasugrel Small molecule 5 mg