Pharmacokinetics of Ceftaroline in Normal and Obese Subjects

Phase 1 Completed 32 enrolled Keith A. Rodvold Forest Laboratories · collab

NaSingle-groupOpen-labelHealth-services research

Summary

The purpose of this study is to characterize plasma and urinary concentrations of ceftaroline following intravenous administration of a single dose of ceftaroline 600 mg in healthy subjects who are normal weight, overweight, and obese.

Timeline

Start: 2012-07
Primary completion: 2013-02
Completion: 2013-02

Publications

Justo JA, Mayer SM, Pai MP, Soriano MM, Danziger LH, Novak RM, Rodvold KA. Pharmacokinetics of ceftaroline in normal body weight and obese (classes I, II, and III) healthy adult subjects. Antimicrob Agents Chemother. 2015 Jul;59(7):3956-65. doi: 10.1128/AAC.00498-15. Epub 2015 Apr 20.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ceftaroline	Other / unclassified	600 mg	Intravenous

Indications

No indication recorded.