drugset / Trial / NCT01649037
To Compare the Efficacy of Nor Adrenaline and Terlipressin vs Step up Terlipressin Therapy in Hepatorenal Syndrome
RandomizedParallel-groupOpen-labelTreatment
Summary
All consecutive patients with liver cirrhosis having Acute Kidney Injury at admission or during hospitalization will be included in the study. The diagnosis of liver cirrhosis will be based on the clinical grounds including Laboratory tests, endoscopic evidence, imaging (Ultrasonography/computed tomography) findings, and liver histology, when available.
Timeline
- Start
- 2012-08
- Primary completion
- 2015-06
- Completion
- 2015-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Noradrenaline | Unknown | 0.5 mg | Intravenous |
| Comparator | Terlipressin | Peptide | 0.5 mg | Intravenous |
| Comparator | Terlipressin | Peptide | 1 mg | Intravenous |
| Comparator | Terlipressin | Peptide | 1.5 mg | Intravenous |