drugset / Trial / NCT01653327

Analgesic Effects of Topical Ketamine Mouthwash in Patients Receiving Chemoradiation or Radiotherapy for Head & Neck Cancer

NCT01653327

Phase 2 Completed 11 enrolled Dartmouth-Hitchcock Medical Center
RandomizedCrossoverQuadruple-blindSupportive care

Summary

* The primary objective is to determine the reduction in pain score by ketamine mouthwash compared to placebo in head and neck cancer patients with refractory mucositis. * The secondary objectives are to describe the duration of analgesia and adverse effects associated with ketamine and placebo.

Timeline

Start
2010-06
Primary completion
2016-08-16
Completion
2016-08-16

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ketamine Small molecule 20 mg Topical