Time to Eradication of Mycoplasma Genitalium and Chlamydia Trachomatis After Treatment Commenced
Summary
The purpose of this on-going study is to study the number of days after antibiotic treatment has commenced (due to infection caused by the sexually transmitted bacteria Chlamydia trachomatis (CT) and Mycoplasma genitalium(Mg)) it takes to be cured i.e to get a negative test result. The specimens are analyzed on first-catch-urine (men) or patient's self-obtained vaginal sample with quantitive nucleic acid amplification test(NAAT). A secondary aim is to detect macrolide resistant Mg-strains and study whether there are any emerging macrolide resistant Mg-strains after treatment with azithromycin. A third aim is to study whether the participating subjects are adherent to the study protocol meaning 12 samples taken during a period of four weeks.
Timeline
- Start
- 2010-02
- Primary completion
- 2015-08
- Completion
- 2016-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Azithromycin | Small molecule | 250 mg | Oral |
| Comparator | Azithromycin | Small molecule | 1 g | Oral |
| Comparator | Doxycycline | Small molecule | 100 mg | Oral |
| Comparator | Lymecycline | Unknown | 300 mg | Oral |